Publication: Codon usage modulates the relationship between the burden and yield of protein overexpression

Expanding a stocastic gene expression simulation to include codon optimization and tRNA abundance validated with experimental growth assays

30 min 5839 words

Published on May 23, 2025 Cameron Roots Cameron Roots's profile picture

Publication: CryptKeeper: a negative design tool for reducing unintentional gene expression in bacteria

A pipeline that predicts gene expression elements in E. coli, with the goal of displaying engineering complications, and tested using prior published case studies

24 min 4727 words

Published on December 02, 2024 Cameron Roots Cameron Roots's profile picture

Publication: OSTIR: open source translation initiation rate prediction

A fork of the RBS Calculator with improved usability and speed

4 min 690 words

Published on September 28, 2022 Cameron Roots Cameron Roots's profile picture

Category : Science

Publication: Codon usage modulates the relationship between the burden and yield of protein overexpression

Publication: CryptKeeper: a negative design tool for reducing unintentional gene expression in bacteria

Publication: OSTIR: open source translation initiation rate prediction